ABSTRACT
Smoking causes diffuse lung diseases with the chemicals it contains. Lung diseases directly related to smoking can be listed as pulmonary Langerhans cell histiocytosis, respiratory bronchiolitis-associated interstitial lung disease, desquamative interstitial pneumonia, and combined pulmonary fibrosis and emphysema. Smoking also causes fibrosis in the alveolar walls, which is called smoking-related interstitial fibrosis or airspace enlargement with fibrosis. It is known that smoking, which causes interstitial fibrosis, also increases the occurrence of non-specific interstitial pneumonia and idiopathic pulmonary fibrosis. If there are typical high-resolution computed tomography findings in the diagnosis of smoking-related lung diseases, diagnosis can be made in some patients without the need for pathological tissue diagnosis. But, both radiological and pathological findings of smoking-related diseases may overlap with each other. Diagnosis may not always be easy, and more than one disease may be seen in the same patient. In this article, smoking-related diffuse lung diseases of epidemiological features, prognosis, clinical, pathological, and radiological findings will be given together and helpful radiological clues in the differential diagnosis will be discussed.
Keywords: Smoking, interstitial fibrosis, high-resolution computed tomography
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